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Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?

Age-related macular degeneration (AMD) is the main reason of blindness in developed countries. Aging is the main AMD risk factor. Oxidative stress, inflammation and some genetic factors play a role in AMD pathogenesis. AMD is associated with the degradation of retinal pigment epithelium (RPE) cells,...

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Detalles Bibliográficos
Autores principales:	Blasiak, Janusz, Piechota, Malgorzata, Pawlowska, Elzbieta, Szatkowska, Magdalena, Sikora, Ewa, Kaarniranta, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687149/ https://www.ncbi.nlm.nih.gov/pubmed/29225722 http://dx.doi.org/10.1155/2017/5293258

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