Cargando…
p300 Knockout Promotes Butyrate Resistance
Dietary fiber is linked to a reduced risk of colorectal cancer (CRC), and this protective activity is likely due to its fermentation product, butyrate. Dependent upon the hyperactivation of Wnt signaling, butyrate represses CRC cell growth and induces apoptosis. However, resistance to butyrate activ...
Autores principales: | Lazarova, Darina L., Bordonaro, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687153/ https://www.ncbi.nlm.nih.gov/pubmed/29151923 http://dx.doi.org/10.7150/jca.21145 |
Ejemplares similares
-
p300 Influences Butyrate-Mediated WNT Hyperactivation In Colorectal Cancer Cells
por: Lazarova, Darina L, et al.
Publicado: (2013) -
Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells
por: Bordonaro, Michael, et al.
Publicado: (2016) -
ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC
por: Lazarova, Darina, et al.
Publicado: (2017) -
Vimentin, colon cancer progression and resistance to butyrate and other HDACis
por: Lazarova, Darina L., et al.
Publicado: (2016) -
Further analysis of p300 in mediating effects of Butyrate in Colorectal Cancer Cells
por: Bordonaro, Michael
Publicado: (2020)