Cargando…

Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1

UDP-glucuronosyltransferase 1A1 (UGT1A1) plays a key role in detoxification of many potentially harmful compounds and drugs. UGT1A1 inhibition may bring risks of drug–drug interactions (DDIs), hyperbilirubinemia and drug-induced liver injury. This study aimed to investigate and compare the inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Xuewei, Lv, Xia, Qu, Hengyan, Li, Dandan, Hu, Mengmeng, Guo, Wenzhi, Ge, Guangbo, Dong, Ruihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687316/ https://www.ncbi.nlm.nih.gov/pubmed/29159025 http://dx.doi.org/10.1016/j.apsb.2017.07.004

Ejemplares similares

Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases
por: Shan, Lina, et al.
Publicado: (2014)

Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term
por: Reimers, Arne, et al.
Publicado: (2010)

Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs
por: Runge-Morris, Melissa, et al.
Publicado: (2009)

Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases
por: Fujiwara, Ryoichi, et al.
Publicado: (2016)

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression
por: Grant, Delores J., et al.
Publicado: (2017)

Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues
por: Zhou, Lucas, et al.
Publicado: (2023)

Effects of Dietary Components on Testosterone Metabolism via UDP-Glucuronosyltransferase
por: Jenkinson, Carl, et al.
Publicado: (2013)

The Inhibition of the Components from Shengmai Injection towards UDP-Glucuronosyltransferase
por: Jiang, Li-Peng, et al.
Publicado: (2014)

Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression
por: Allain, Eric P., et al.
Publicado: (2020)

Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis
por: Zeng, Wanying, et al.
Publicado: (2022)

Is Ceftriaxone-Induced Biliary Pseudolithiasis Influenced by UDP-Glucuronosyltransferase 1A1 Gene Polymorphisms?
por: Fretzayas, Andrew, et al.
Publicado: (2011)

Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview
por: Guillemette, Chantal, et al.
Publicado: (2004)

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication
por: Ouzzine, Mohamed, et al.
Publicado: (2014)

Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk
por: Wang, J, et al.
Publicado: (2013)

Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics
por: Rouleau, Michèle, et al.
Publicado: (2017)

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
por: Neumann, Elizabeth, et al.
Publicado: (2016)

Thiamethoxam Resistance in Aphis gossypii Glover Relies on Multiple UDP-Glucuronosyltransferases
por: Pan, Yiou, et al.
Publicado: (2018)

Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice
por: Böhmdorfer, Michaela, et al.
Publicado: (2017)

Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)
por: Zhang, Xu-Xin, et al.
Publicado: (2017)

Characterization of UDP-Glucuronosyltransferases and the Potential Contribution to Nicotine Tolerance in Myzus persicae
por: Pan, Yiou, et al.
Publicado: (2019)

Machine learning and structure-based modeling for the prediction of UDP-glucuronosyltransferase inhibition
por: Dudas, Balint, et al.
Publicado: (2022)

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia
por: Aoshima, Naoya, et al.
Publicado: (2014)

Role of UDP-Glucuronosyltransferase 1A1 in the Metabolism and Pharmacokinetics of Silymarin Flavonolignans in Patients with HCV and NAFLD
por: Xie, Ying, et al.
Publicado: (2017)

Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes
por: Kutsuno, Yuki, et al.
Publicado: (2013)

Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1
por: Pang, Hui-Lin, et al.
Publicado: (2022)

Sequentially administrated of pemetrexed with icotinib/erlotinib in lung adenocarcinoma cell lines in vitro
por: Feng, Xiuli, et al.
Publicado: (2017)

Inhibitory effects of UDP-glucuronosyltransferase (UGT) typical ligands against E. coli beta-glucuronidase (GUS)
por: Xiao, Ling, et al.
Publicado: (2020)

Polymorphic Expression of UDP-Glucuronosyltransferase UGTlA Gene in Human Colorectal Cancer
por: Wang, Min, et al.
Publicado: (2013)

Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells
por: Dellinger, Ryan W., et al.
Publicado: (2012)

Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
por: Greer, Aleksandra K., et al.
Publicado: (2014)

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development
por: YABUSAKI, Risa, et al.
Publicado: (2015)

Inhibitory Effect of Sauchinone on UDP-Glucuronosyltransferase (UGT) 2B7 Activity
por: You, Byoung Hoon, et al.
Publicado: (2018)

UDP‐glucuronosyltransferase polymorphisms affect diethylnitrosamine‐induced carcinogenesis in humanized transgenic mice
por: Landerer, Steffen, et al.
Publicado: (2020)

Intestinal UDP-glucuronosyltransferase as a potential target for the treatment and prevention of lymphatic filariasis
por: Flynn, Alexander F., et al.
Publicado: (2019)

The Functionality of UDP-Glucuronosyltransferase Genetic Variants and their Association with Drug Responses and Human Diseases
por: Jarrar, Yazun, et al.
Publicado: (2021)

Association of NQO2 With UDP-Glucuronosyltransferases Reduces Menadione Toxicity in Neuroblastoma Cells
por: Chhour, Monivan, et al.
Publicado: (2021)

Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences
por: Chen, Juan, et al.
Publicado: (2023)

Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia
por: Shibuya, Ayako, et al.
Publicado: (2013)

Genetic Polymorphisms of the UDP‐Glucuronosyltransferase 1A7 Gene and Irinotecan Toxicity in Japanese Cancer Patients
por: Ando, Maki, et al.
Publicado: (2002)

Genetic polymorphisms in human UDP-glucuronosyltransferases 1A7 and the risk of gastrointestinal carcinomas: A systematic review and network meta-analysis
por: Zhang, Yingshi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_l0hc5f7rt0b5ed7gq8i4hs3elb