The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials

The alpha-7 nicotinic acetylcholine receptor (α7 nAChR), consisting of homomeric α7 subunits, is a ligand-gated Ca(2+)-permeable ion channel implicated in cognition and neuropsychiatric disorders. Enhancement of α7 nAChR function is considered to be a potential therapeutic strategy aiming at amelior...

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Detalles Bibliográficos
Autores principales: Yang, Taoyi, Xiao, Ting, Sun, Qi, Wang, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687317/
https://www.ncbi.nlm.nih.gov/pubmed/29159020
http://dx.doi.org/10.1016/j.apsb.2017.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687317/
https://www.ncbi.nlm.nih.gov/pubmed/29159020
http://dx.doi.org/10.1016/j.apsb.2017.09.001

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