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Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect

With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits. Host immunity, tumor microenvironment and abnormal vascularity contribute to inefficient vector delivery. A number...

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Detalles Bibliográficos
Autores principales: Yokoda, Raquel, Nagalo, Bolni M, Vernon, Brent, Oklu, Rahmi, Albadawi, Hassan, DeLeon, Thomas T, Zhou, Yumei, Egan, Jan B, Duda, Dan G, Borad, Mitesh J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687448/
https://www.ncbi.nlm.nih.gov/pubmed/29184854
http://dx.doi.org/10.2147/OV.S145262

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