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Lacrimal drainage anomalies in congenital rubella syndrome
PURPOSE: The objective of this study was to ascertain the lacrimal drainage anomalies in a cohort of patients suffering from congenital rubella syndrome (CRS). METHODS: This was a retrospective case series performed in patients with CRS presenting with associated lacrimal drainage anomalies (LDA) ov...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687484/ https://www.ncbi.nlm.nih.gov/pubmed/29184387 http://dx.doi.org/10.2147/OPTH.S149111 |
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author | Gupta, Shweta Ali, Mohammad Javed Naik, Milind N |
author_facet | Gupta, Shweta Ali, Mohammad Javed Naik, Milind N |
author_sort | Gupta, Shweta |
collection | PubMed |
description | PURPOSE: The objective of this study was to ascertain the lacrimal drainage anomalies in a cohort of patients suffering from congenital rubella syndrome (CRS). METHODS: This was a retrospective case series performed in patients with CRS presenting with associated lacrimal drainage anomalies (LDA) over 6 years from 2011 to 2016. All the patients were confirmed as having CRS after clinical and laboratory testing. Data collected include demographics; associated lacrimal, ocular, and systemic anomalies; interventions performed for lacrimal anomalies; and their anatomical and functional outcomes. RESULTS: Eighty five patients were diagnosed as having CRS during the study period, and of these 23 eyes of 12 patients with associated LDA were included in the study. The prevalence of LDA was 14% in CRS. The mean age at presentation was 15.5 weeks, and all except one had bilateral presentation. Seventeen eyes were diagnosed with simple congenital nasolacrimal duct obstruction (CNLDO) and the remaining six eyes had complex CNLDO with buried probes. Additional lacrimal anomalies noted in the six complex CNLDO cases included punctal agenesis (n=3), atonic sac (n=3), incomplete punctal canalization (n=2), and single canalicular wall hypoplasia (n=1). At a mean follow-up of 12.54 months, anatomical and functional success were noted in 91.3% (21/23 eyes). CONCLUSION: Simple CNLDO was the most common of the LDA in CRS. Buried probe was universal among the cases with complex CNLDO. All CRS patients should be screened for lacrimal anomalies to initiate appropriate interventions for successful outcomes. |
format | Online Article Text |
id | pubmed-5687484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56874842017-11-28 Lacrimal drainage anomalies in congenital rubella syndrome Gupta, Shweta Ali, Mohammad Javed Naik, Milind N Clin Ophthalmol Original Research PURPOSE: The objective of this study was to ascertain the lacrimal drainage anomalies in a cohort of patients suffering from congenital rubella syndrome (CRS). METHODS: This was a retrospective case series performed in patients with CRS presenting with associated lacrimal drainage anomalies (LDA) over 6 years from 2011 to 2016. All the patients were confirmed as having CRS after clinical and laboratory testing. Data collected include demographics; associated lacrimal, ocular, and systemic anomalies; interventions performed for lacrimal anomalies; and their anatomical and functional outcomes. RESULTS: Eighty five patients were diagnosed as having CRS during the study period, and of these 23 eyes of 12 patients with associated LDA were included in the study. The prevalence of LDA was 14% in CRS. The mean age at presentation was 15.5 weeks, and all except one had bilateral presentation. Seventeen eyes were diagnosed with simple congenital nasolacrimal duct obstruction (CNLDO) and the remaining six eyes had complex CNLDO with buried probes. Additional lacrimal anomalies noted in the six complex CNLDO cases included punctal agenesis (n=3), atonic sac (n=3), incomplete punctal canalization (n=2), and single canalicular wall hypoplasia (n=1). At a mean follow-up of 12.54 months, anatomical and functional success were noted in 91.3% (21/23 eyes). CONCLUSION: Simple CNLDO was the most common of the LDA in CRS. Buried probe was universal among the cases with complex CNLDO. All CRS patients should be screened for lacrimal anomalies to initiate appropriate interventions for successful outcomes. Dove Medical Press 2017-11-09 /pmc/articles/PMC5687484/ /pubmed/29184387 http://dx.doi.org/10.2147/OPTH.S149111 Text en © 2017 Gupta et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Gupta, Shweta Ali, Mohammad Javed Naik, Milind N Lacrimal drainage anomalies in congenital rubella syndrome |
title | Lacrimal drainage anomalies in congenital rubella syndrome |
title_full | Lacrimal drainage anomalies in congenital rubella syndrome |
title_fullStr | Lacrimal drainage anomalies in congenital rubella syndrome |
title_full_unstemmed | Lacrimal drainage anomalies in congenital rubella syndrome |
title_short | Lacrimal drainage anomalies in congenital rubella syndrome |
title_sort | lacrimal drainage anomalies in congenital rubella syndrome |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687484/ https://www.ncbi.nlm.nih.gov/pubmed/29184387 http://dx.doi.org/10.2147/OPTH.S149111 |
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