Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation

Glomerular podocytes are able to transdifferentiate under disease conditions, acquire de novo immune phenotypes and behave as immunocompetent cells, like phagocytes or antigen-presenting cells. Upon stimulation with lipopolysaccharide (LPS), a prototypical pathogen-associated molecular pattern, podo...

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Detalles Bibliográficos
Autores principales: Wang, Pei, Zhou, Sijie, Ge, Yan, Lu, Minglei, Liu, Zhangsuo, Gong, Rujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687608/
https://www.ncbi.nlm.nih.gov/pubmed/29179438
http://dx.doi.org/10.18632/oncotarget.19917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687608/
https://www.ncbi.nlm.nih.gov/pubmed/29179438
http://dx.doi.org/10.18632/oncotarget.19917

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