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Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation
Glomerular podocytes are able to transdifferentiate under disease conditions, acquire de novo immune phenotypes and behave as immunocompetent cells, like phagocytes or antigen-presenting cells. Upon stimulation with lipopolysaccharide (LPS), a prototypical pathogen-associated molecular pattern, podo...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687608/ https://www.ncbi.nlm.nih.gov/pubmed/29179438 http://dx.doi.org/10.18632/oncotarget.19917 |