The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth

The Hippo pathway regulates organ size, growth and comprises several tumor related factors, including the oncoprotein YAP1 and the tumor suppressor RASSF1A. RASSF1A is frequently epigenetically inactivated in cancer. In our study, we analyzed the effect of RASSF1A on the function of YAP1. Expression...

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Detalles Bibliográficos
Autores principales: Jiménez, Adriana P., Traum, Annalena, Boettger, Thomas, Hackstein, Holger, Richter, Antje M., Dammann, Reinhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687617/
https://www.ncbi.nlm.nih.gov/pubmed/29179447
http://dx.doi.org/10.18632/oncotarget.18177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687617/
https://www.ncbi.nlm.nih.gov/pubmed/29179447
http://dx.doi.org/10.18632/oncotarget.18177

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