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GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression

Zinc finger protein 281 (ZNF281) has been recently shown to be critical for CRC progression. However, the immediate upstream regulators of ZNF281 remain unclear. Here we reported that the E3 ligase the β-transducin repeat-containing protein 2 (β-TrCP2) governs the ubiquitination and degradation of Z...

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Detalles Bibliográficos
Autores principales:	Zhu, Yuekun, Zhou, Qingxin, Zhu, Guiling, Xing, Yanwei, Li, Shiqiang, Ren, Niansheng, Liu, Tianyou, Zhu, Anlong, Bai, Yuxian, Piao, Daxun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687630/ https://www.ncbi.nlm.nih.gov/pubmed/29179460 http://dx.doi.org/10.18632/oncotarget.20100

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