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Notochordal-cell derived extracellular vesicles exert regenerative effects on canine and human nucleus pulposus cells

During intervertebral disc ageing, chondrocyte-like cells (CLCs) replace notochordal cells (NCs). NCs have been shown to induce regenerative effects in CLCs. Since vesicles released by NCs may be responsible for these effects, we characterized NC-derived extracellular vesicles (EVs) and determined t...

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Detalles Bibliográficos
Autores principales:	Bach, Frances, Libregts, Sten, Creemers, Laura, Meij, Björn, Ito, Keita, Wauben, Marca, Tryfonidou, Marianna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687651/ https://www.ncbi.nlm.nih.gov/pubmed/29179481 http://dx.doi.org/10.18632/oncotarget.21483

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