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Sphingosine kinase 1 mediates diabetic renal fibrosis via NF-κB signaling pathway: involvement of CK2α

Sphingosine kinase 1 (SphK1) plays a pivotal role in regulating diabetic renal fibrotic factors such as fibronectin (FN) and intercellular adhesion molecule-1 (ICAM-1). Especially, activation of SphK1 is closely linked to the body inflammatory reaction. Casein kinase 2α subunit (CK2α), a protein kin...

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Detalles Bibliográficos
Autores principales:	Huang, Junying, Li, Jingyan, Chen, Zhiquan, Li, Jie, Chen, Qiuhong, Gong, Wenyan, Liu, Peiqing, Huang, Heqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687663/ https://www.ncbi.nlm.nih.gov/pubmed/29179493 http://dx.doi.org/10.18632/oncotarget.21640

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