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Selection for avian leukosis virus integration sites determines the clonal progression of B-cell lymphomas

Avian leukosis virus (ALV) is a simple retrovirus that causes a wide range of tumors in chickens, the most common of which are B-cell lymphomas. The viral genome integrates into the host genome and uses its strong promoter and enhancer sequences to alter the expression of nearby genes, frequently in...

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Detalles Bibliográficos
Autores principales: Malhotra, Sanandan, Winans, Shelby, Lam, Gary, Justice, James, Morgan, Robin, Beemon, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687753/
https://www.ncbi.nlm.nih.gov/pubmed/29099869
http://dx.doi.org/10.1371/journal.ppat.1006708