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Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow
The recent progress in bioengineering has created great interest in the dynamics and manipulation of long, deformable macromolecules interacting with fluid flow. We report experimental data on the cross-flow migration, bending, and buckling of extremely deformable hydrogel nanofilaments conveyed by...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687761/ https://www.ncbi.nlm.nih.gov/pubmed/29141043 http://dx.doi.org/10.1371/journal.pone.0187815 |
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author | Pawłowska, Sylwia Nakielski, Paweł Pierini, Filippo Piechocka, Izabela K. Zembrzycki, Krzysztof Kowalewski, Tomasz A. |
author_facet | Pawłowska, Sylwia Nakielski, Paweł Pierini, Filippo Piechocka, Izabela K. Zembrzycki, Krzysztof Kowalewski, Tomasz A. |
author_sort | Pawłowska, Sylwia |
collection | PubMed |
description | The recent progress in bioengineering has created great interest in the dynamics and manipulation of long, deformable macromolecules interacting with fluid flow. We report experimental data on the cross-flow migration, bending, and buckling of extremely deformable hydrogel nanofilaments conveyed by an oscillatory flow into a microchannel. The changes in migration velocity and filament orientation are related to the flow velocity and the filament’s initial position, deformation, and length. The observed migration dynamics of hydrogel filaments qualitatively confirms the validity of the previously developed worm-like bead-chain hydrodynamic model. The experimental data collected may help to verify the role of hydrodynamic interactions in molecular simulations of long molecular chains dynamics. |
format | Online Article Text |
id | pubmed-5687761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-56877612017-11-30 Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow Pawłowska, Sylwia Nakielski, Paweł Pierini, Filippo Piechocka, Izabela K. Zembrzycki, Krzysztof Kowalewski, Tomasz A. PLoS One Research Article The recent progress in bioengineering has created great interest in the dynamics and manipulation of long, deformable macromolecules interacting with fluid flow. We report experimental data on the cross-flow migration, bending, and buckling of extremely deformable hydrogel nanofilaments conveyed by an oscillatory flow into a microchannel. The changes in migration velocity and filament orientation are related to the flow velocity and the filament’s initial position, deformation, and length. The observed migration dynamics of hydrogel filaments qualitatively confirms the validity of the previously developed worm-like bead-chain hydrodynamic model. The experimental data collected may help to verify the role of hydrodynamic interactions in molecular simulations of long molecular chains dynamics. Public Library of Science 2017-11-15 /pmc/articles/PMC5687761/ /pubmed/29141043 http://dx.doi.org/10.1371/journal.pone.0187815 Text en © 2017 Pawłowska et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Pawłowska, Sylwia Nakielski, Paweł Pierini, Filippo Piechocka, Izabela K. Zembrzycki, Krzysztof Kowalewski, Tomasz A. Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title | Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title_full | Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title_fullStr | Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title_full_unstemmed | Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title_short | Lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
title_sort | lateral migration of electrospun hydrogel nanofilaments in an oscillatory flow |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687761/ https://www.ncbi.nlm.nih.gov/pubmed/29141043 http://dx.doi.org/10.1371/journal.pone.0187815 |
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