Cargando…

Effect of Tirapazamine, Metformin or Mild Hyperthermia on Recovery From Radiation-Induced Damage in Pimonidazole-Unlabeled Quiescent Tumor Cells

BACKGROUND: The aim of the study was to examine the effect of tirapazamine (TPZ) on recovery from radiation-induced damage in pimonidazole-unlabeled quiescent (Q) tumor cells compared with that of metformin (Met) or mild temperature hyperthermia (MTH). METHODS: Proliferating (P) cells in EL4 tumors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masunaga, Shin-ichiro, Tano, Keizo, Sanada, Yu, Sakurai, Yoshinori, Tanaka, Hiroki, Suzuki, Minoru, Kondo, Natsuko, Watanabe, Tsubasa, Takata, Takushi, Maruhashi, Akira, Ono, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elmer Press 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687893/ https://www.ncbi.nlm.nih.gov/pubmed/29147450 http://dx.doi.org/10.14740/wjon1058w

Ejemplares similares

Wortmannin efficiently suppresses the recovery from radiation-induced damage in pimonidazole-unlabeled quiescent tumor cell population
por: Masunaga, Shin-ichiro, et al.
Publicado: (2013)

Radiosensitivity and Capacity to Recover from Radiation-Induced Damage in Pimonidazole-Unlabeled Intratumor Quiescent Cells Depend on p53 Status
por: Masunaga, Shin-ichiro, et al.
Publicado: (2011)

An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed (10)B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness
por: Masunaga, Shin-ichiro, et al.
Publicado: (2020)

The Effect of p53 Status on Radio-Sensitivity of Quiescent Tumor Cell Population Irradiated With γ-Rays at Various Dose Rates
por: Masunaga, Shin-ichiro, et al.
Publicado: (2018)

Significance of Fractionated Administration of Thalidomide Combined With γ-Ray Irradiation in Terms of Local Tumor Response and Lung Metastasis
por: Masunaga, Shin-ichiro, et al.
Publicado: (2014)

Effects of Bioreductive Agents, Tirapazamine and Mitomycin C, on Quiescent Cell Populations in Solid Tumors, Evaluated by Micronucleus Assay
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1997)

Applicability of Combination with Tirapazamine in Boron Neutron Capture Therapy
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1998)

Effect of bevacizumab combined with boron neutron capture therapy on local tumor response and lung metastasis
por: MASUNAGA, SHIN-ICHIRO, et al.
Publicado: (2014)

The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy
por: Masunaga, Shin-ichiro, et al.
Publicado: (2014)

Usefulness of Daily Fractionated Administration of Wortmannin Combined With γ-Ray Irradiation in Terms of Local Tumor Response and Lung Metastasis
por: Masunaga, Shin-ichiro, et al.
Publicado: (2013)

Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo‐chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells
por: Masunaga, Shin‐ichiro, et al.
Publicado: (2000)

Effects of p53 Status of Tumor Cells and Combined Treatment With Mild Hyperthermia, Wortmannin or Caffeine on Recovery From Radiation-Induced Damage
por: Masunaga, Shin-ichiro, et al.
Publicado: (2019)

The Effect of p53 Status of Tumor Cells on Radiosensitivity of Irradiated Tumors With Carbon-Ion Beams Compared With γ-Rays or Reactor Neutron Beams
por: Masunaga, Shin-ichiro, et al.
Publicado: (2015)

Augmentation in Chemosensitivity of Intratumor Quiescent Cells by Combined Treatment with Nicotinamide and Mild Hyperthermia
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1997)

The impact of TP53 status of tumor cells including the type and the concentration of administered (10)B delivery agents on compound biological effectiveness in boron neutron capture therapy
por: Masunaga, Shin-ichiro, et al.
Publicado: (2023)

Changes in the Sensitivity of Intratumor Cells during Fractionated Tirapazamine Administration
por: Masunaga, Shin‐ichiro, et al.
Publicado: (2000)

Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice.
por: Walton, M. I., et al.
Publicado: (1989)

Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells
por: Kadoda, Kei, et al.
Publicado: (2017)

Responses of Total and Quiescent Cell Populations in Solid Tumors to Boron and Gadolinium Neutron Capture Reaction Using Neutrons with Two Different Energy Spectra
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1998)

Tirapazamine-cisplatin: the synergy.
por: Gatzemeier, U., et al.
Publicado: (1998)

Development of a simple and rapid method of precisely identifying the position of (10)B atoms in tissue: an improvement in standard alpha autoradiography
por: Tanaka, Hiroki, et al.
Publicado: (2014)

Evaluating the Usefulness of a Novel (10)B-Carrier Conjugated With Cyclic RGD Peptide in Boron Neutron Capture Therapy
por: Masunaga, Shin-ichiro, et al.
Publicado: (2012)

Reduction of hypoxic cells in solid tumours induced by mild hyperthermia: special reference to differences in changes in the hypoxic fraction between total and quiescent cell populations.
por: Masunaga, S., et al.
Publicado: (1997)

Distribution of pimonidazole and RSU 1069 in tumour and normal tissues.
por: Cobb, L. M., et al.
Publicado: (1990)

Impact of the p53 Status of the Tumor Cells on the Effect of Reactor Neutron Beam Irradiation, with Emphasis on the Response of Intratumor Quiescent Cells
por: Masunaga, Shin‐ichiro, et al.
Publicado: (2002)

Evaluation of the Potential of p‐Boronophenylalaninol as a Boron Carrier in Boron Neutron Capture Therapy, Referring to the Effect on Intratumor Quiescent Cells
por: Masunaga, Shin‐ichiro, et al.
Publicado: (2001)

Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia
por: Olive, P L, et al.
Publicado: (2000)

Electronic structure and reactivity of tirapazamine as a radiosensitizer
por: Romero, José, et al.
Publicado: (2021)

Alteration of Radiosensitivity of Quiescent Cell Populations in Solid Tumors Irradiated with X‐Rays Twice at Various Intervals
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1993)

Development and Validation of a Kilogram-Scale Synthesis of Tirapazamine
por: Lienard, Philippe, et al.
Publicado: (2020)

Pimonidazole binding in C6 rat brain glioma: relation with lipid droplet detection
por: Zoula, S, et al.
Publicado: (2003)

Exploiting tumour hypoxia and overcoming mutant p53 with tirapazamine.
por: Brown, J. M.
Publicado: (1998)

Redox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells
por: Nemeikaitė-Čėnienė, Aušra, et al.
Publicado: (2023)

Intensity-modulated irradiation for superficial tumors by overlapping irradiation fields using intensity modulators in accelerator-based BNCT
por: Sasaki, Akinori, et al.
Publicado: (2022)

Development of optimization method for uniform dose distribution on superficial tumor in an accelerator-based boron neutron capture therapy system
por: Sasaki, Akinori, et al.
Publicado: (2023)

Classification of unlabeled online media
por: Prakash, Sakthi Kumar Arul, et al.
Publicado: (2021)

Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver.
por: Arteel, G. E., et al.
Publicado: (1995)

The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
por: Ragnum, H B, et al.
Publicado: (2015)

Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole
por: Dhani, N C, et al.
Publicado: (2015)

Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia
por: Masaki, Yukiko, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rjuu9kj4gbbkoej1ceujks1o69