Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

Coronaviruses (CoVs) encode a mixture of highly conserved and novel genes, as well as genetic elements necessary for infection and pathogenesis, raising the possibility of common targets for attenuation and therapeutic design. In this study, we focused on highly conserved nonstructural protein 16 (N...

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Detalles Bibliográficos
Autores principales: Menachery, Vineet D., Gralinski, Lisa E., Mitchell, Hugh D., Dinnon, Kenneth H., Leist, Sarah R., Yount, Boyd L., Graham, Rachel L., McAnarney, Eileen T., Stratton, Kelly G., Cockrell, Adam S., Debbink, Kari, Sims, Amy C., Waters, Katrina M., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687918/
https://www.ncbi.nlm.nih.gov/pubmed/29152578
http://dx.doi.org/10.1128/mSphere.00346-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687918/
https://www.ncbi.nlm.nih.gov/pubmed/29152578
http://dx.doi.org/10.1128/mSphere.00346-17

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