Cargando…

Inhibition of Retrograde Transport Limits Polyomavirus Infection In Vivo

Polyomaviruses (PyVs) silently infect most humans, but they can cause life-threatening diseases in immunocompromised individuals. The JC polyomavirus (JCPyV) induces progressive multifocal leukoencephalopathy, a severe demyelinating disease in multiple sclerosis patients receiving immunomodulatory t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maru, Saumya, Jin, Ge, Desai, Dhimant, Amin, Shantu, Shwetank, Lauver, Matthew D., Lukacher, Aron E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687923/ https://www.ncbi.nlm.nih.gov/pubmed/29152583 http://dx.doi.org/10.1128/mSphereDirect.00494-17

Ejemplares similares

T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus
por: Lauver, Matthew D, et al.
Publicado: (2022)

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection
por: Mockus, Taryn E., et al.
Publicado: (2018)

JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy: Altering Tropism or Mediating Immune Evasion?
por: Lauver, Matthew D., et al.
Publicado: (2020)

TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection
por: Maru, Saumya, et al.
Publicado: (2017)

Antibody escape by polyomavirus capsid mutation facilitates neurovirulence
por: Lauver, Matthew D, et al.
Publicado: (2020)

Polyomavirus Wakes Up and Chooses Neurovirulence
por: Butic, Arrienne B., et al.
Publicado: (2023)

PD-1 Dynamically Regulates Inflammation and Development of Brain-Resident Memory CD8 T Cells During Persistent Viral Encephalitis
por: Shwetank,, et al.
Publicado: (2019)

Notch Activation Is Dispensable for D, L-Sulforaphane-Mediated Inhibition of Human Prostate Cancer Cell Migration
por: Hahm, Eun-Ryeong, et al.
Publicado: (2012)

To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections
por: Mockus, Taryn E., et al.
Publicado: (2019)

Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain
por: Pham, Alexander M., et al.
Publicado: (2023)

The Oxindole GW-5074 Inhibits JC Polyomavirus Infection and Spread by Antagonizing the MAPK-ERK Signaling Pathway
por: Kaiserman, Jacob, et al.
Publicado: (2023)

Targeting Protein Translation in Melanoma by Inhibiting EEF-2 Kinase Regulates Cholesterol Metabolism though SREBP2 to Inhibit Tumour Development
por: Dinavahi, Saketh S., et al.
Publicado: (2022)

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells
por: Li, Jingxia, et al.
Publicado: (2004)

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells
por: Li, Jingxia, et al.
Publicado: (2009)

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249
por: Weng, Mao-Wen, et al.
Publicado: (2017)

A Retrograde Trafficking Inhibitor of Ricin and Shiga-Like Toxins Inhibits Infection of Cells by Human and Monkey Polyomaviruses
por: Nelson, Christian D. S., et al.
Publicado: (2013)

Maintenance of PD‐1 on brain‐resident memory CD8 T cells is antigen independent
por: Shwetank,, et al.
Publicado: (2017)

Efficient Synthesis for Altering Side Chain Length on Cannabinoid Molecules and Their Effects in Chemotherapy and Chemotherapeutic Induced Neuropathic Pain
por: Raup-Konsavage, Wesley M., et al.
Publicado: (2022)

Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury
por: Kim, Steven C., et al.
Publicado: (2017)

Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases
por: Kale, Vijay Pralhad, et al.
Publicado: (2023)

Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention
por: Tellez, Carmen S., et al.
Publicado: (2021)

Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport
por: Yermakova, Anastasiya, et al.
Publicado: (2014)

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
por: Jiang, Changtao, et al.
Publicado: (2015)

In Vivo Imaging of Anterograde and Retrograde Axonal Transport in Rodent Peripheral Nerves
por: Sleigh, James N., et al.
Publicado: (2020)

Imaging Net Retrograde Axonal Transport In Vivo: A Physiological Biomarker
por: Lee, Pin‐Tsun Justin, et al.
Publicado: (2022)

A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer
por: Tagaram, Hephzibah Rani S., et al.
Publicado: (2016)

The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation
por: Nettleford, Shaneice K., et al.
Publicado: (2020)

In Vitro and In Vivo Models for the Study of Human Polyomavirus Infection
por: Barth, Heidi, et al.
Publicado: (2016)

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation
por: van den Bogaard, Ellen, et al.
Publicado: (2015)

Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice
por: Jiang, Jie, et al.
Publicado: (2022)

Genome Sequences of a Rat Polyomavirus Related to Murine Polyomavirus, Rattus norvegicus Polyomavirus 1
por: Ehlers, Bernhard, et al.
Publicado: (2015)

Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport
por: Gowda, Raghavendra, et al.
Publicado: (2017)

Insights into anti-tumor immunity via the polyomavirus shared across human Merkel cell carcinomas
por: Jani, Saumya, et al.
Publicado: (2023)

In vivo effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract
por: Fang, Zhong-Ze, et al.
Publicado: (2014)

Hamburger polyomaviruses
por: Peretti, Alberto, et al.
Publicado: (2015)

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia
por: Annageldiyev, Charyguly, et al.
Publicado: (2020)

Human Polyomavirus Related to African Green Monkey Lymphotropic Polyomavirus
por: Sauvage, Virginie, et al.
Publicado: (2011)

Novel human polyomaviruses, Merkel cell polyomavirus and human polyomavirus 9, in Japanese chronic lymphocytic leukemia cases
por: Imajoh, Masayuki, et al.
Publicado: (2012)

Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma
por: Toptan, Tuna, et al.
Publicado: (2018)

The Importance of Mouse Models to Define Immunovirologic Determinants of Progressive Multifocal Leukoencephalopathy
por: Frost, Elizabeth L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6b961v50qoo81iho3d6lq230ep