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Genetic polymorphism related to monocyte-macrophage function is associated with graft-versus-host disease

Despite detailed human leukocyte antigen (HLA) matching and modern immunosuppressive therapy, severe graft-versus-host disease (GvHD) remains a major hurdle for successful allogeneic hematopoietic stem cell transplantation (HSCT). As the genetic diversity in GvHD complicates the systematic discovery...

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Detalles Bibliográficos
Autores principales:	Hyvärinen, Kati, Ritari, Jarmo, Koskela, Satu, Niittyvuopio, Riitta, Nihtinen, Anne, Volin, Liisa, Gallardo, David, Partanen, Jukka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688060/ https://www.ncbi.nlm.nih.gov/pubmed/29142307 http://dx.doi.org/10.1038/s41598-017-15915-3

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