A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

The NUDIX enzymes are involved in cellular metabolism and homeostasis, as well as mRNA processing. Although highly conserved throughout all organisms, their biological roles and biochemical redundancies remain largely unclear. To address this, we globally resolve their individual properties and inte...

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Detalles Bibliográficos
Autores principales: Carreras-Puigvert, Jordi, Zitnik, Marinka, Jemth, Ann-Sofie, Carter, Megan, Unterlass, Judith E., Hallström, Björn, Loseva, Olga, Karem, Zhir, Calderón-Montaño, José Manuel, Lindskog, Cecilia, Edqvist, Per-Henrik, Matuszewski, Damian J., Ait Blal, Hammou, Berntsson, Ronnie P. A., Häggblad, Maria, Martens, Ulf, Studham, Matthew, Lundgren, Bo, Wählby, Carolina, Sonnhammer, Erik L. L., Lundberg, Emma, Stenmark, Pål, Zupan, Blaz, Helleday, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688067/
https://www.ncbi.nlm.nih.gov/pubmed/29142246
http://dx.doi.org/10.1038/s41467-017-01642-w

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