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TDP-43 misexpression causes defects in dendritic growth

Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) share overlapping genetic causes and disease symptoms, and are linked neuropathologically by the RNA binding protein TDP-43 (TAR DNA binding protein-43 kDa). TDP-43 regulates RNA metabolism, trafficking, and localization of thousa...

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Detalles Bibliográficos
Autores principales:	Herzog, Josiah J., Deshpande, Mugdha, Shapiro, Leah, Rodal, Avital A., Paradis, Suzanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688077/ https://www.ncbi.nlm.nih.gov/pubmed/29142232 http://dx.doi.org/10.1038/s41598-017-15914-4

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