A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure

In humans, germline mutations in Trpm6 cause autosomal dominant hypomagnesemia with secondary hypocalcemia disorder. Loss of Trpm6 in mice also perturbs cellular magnesium homeostasis but additionally results in early embryonic lethality and neural tube closure defects. To define the mechanisms by w...

Descripción completa

Detalles Bibliográficos
Autores principales: Komiya, Yuko, Bai, Zhiyong, Cai, Na, Lou, Liping, Al-Saadi, Namariq, Mezzacappa, Courtney, Habas, Raymond, Runnels, Loren W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688082/
https://www.ncbi.nlm.nih.gov/pubmed/29142255
http://dx.doi.org/10.1038/s41598-017-15855-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688082/
https://www.ncbi.nlm.nih.gov/pubmed/29142255
http://dx.doi.org/10.1038/s41598-017-15855-y

Ejemplares similares