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5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins
Glioblastoma (GBM) contains diverse microenvironments with uneven distributions of oncogenic alterations and signaling networks. The diffusely infiltrative properties of GBM result in residual tumor at neurosurgical resection margins, representing the source of relapse in nearly all cases and sugges...
Autores principales: | Ross, James L., Cooper, Lee A. D., Kong, Jun, Gutman, David, Williams, Merete, Tucker-Burden, Carol, McCrary, Myles R., Bouras, Alexandros, Kaluzova, Milota, Dunn, William D., Duong, Duc, Hadjipanayis, Constantinos G., Brat, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688093/ https://www.ncbi.nlm.nih.gov/pubmed/29142297 http://dx.doi.org/10.1038/s41598-017-15849-w |
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