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Fluid Retention Caused by Rosiglitazone Is Related to Increases in AQP2 and αENaC Membrane Expression

Peroxisome proliferator activated receptor-γ (PPARγ) is a ligand-activated transcription factor of the nuclear hormone receptor superfamily. The decreased phosphorylation of PPARγ due to rosiglitazone (ROS) is the main reason for the increased insulin sensitivity caused by this antidiabetic drug. Ho...

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Detalles Bibliográficos
Autores principales: Xu, Jinghua, Pan, Mingyue, Wang, Xiaoli, Xu, Lishi, Li, Lanfang, Xu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688369/
https://www.ncbi.nlm.nih.gov/pubmed/29230238
http://dx.doi.org/10.1155/2017/8130968

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