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Hepatic paragonimiasis in a 15-month-old girl: a case report

BACKGROUND: Paragonimiasis, particularly hepatic paragonimiasis (HP), is a type of zoonotic parasitic disease rarely encountered in infants. There have been only a few reports of HP, and no case of HP has been reported in an infant. CASE PRESENTATION: A 15-month-old girl presented with persistent mi...

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Autores principales: Gong, Zongrong, Xu, Zhicheng, Lei, Chuanfen, Wan, Chaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688620/
https://www.ncbi.nlm.nih.gov/pubmed/29141594
http://dx.doi.org/10.1186/s12887-017-0942-5
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author Gong, Zongrong
Xu, Zhicheng
Lei, Chuanfen
Wan, Chaomin
author_facet Gong, Zongrong
Xu, Zhicheng
Lei, Chuanfen
Wan, Chaomin
author_sort Gong, Zongrong
collection PubMed
description BACKGROUND: Paragonimiasis, particularly hepatic paragonimiasis (HP), is a type of zoonotic parasitic disease rarely encountered in infants. There have been only a few reports of HP, and no case of HP has been reported in an infant. CASE PRESENTATION: A 15-month-old girl presented with persistent mild fever with a duration of 1 month, hepatomegaly, and low-density lesions in the right hepatic lobe on abdominal ultrasound and computer tomography. Pathological examination and serum antibody detection were performed to verify HP. The diagnosis of HP was established based on findings of Charcot-Leyden crystals on liver lesion biopsy and antibodies against paragonimus westermani detected by enzyme-linked immunosorbent assay. After initiation of praziquantel (75 mg/kg/day for 3 days), all clinical findings promptly improved and the patient was discharged. CONCLUSION: It is very important to consider paragonimiasis in the clinical examination of infants from an area with paragonimiasis epidemic presenting with fever, hepatomegaly, low-density lesions in the liver.
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spelling pubmed-56886202017-11-22 Hepatic paragonimiasis in a 15-month-old girl: a case report Gong, Zongrong Xu, Zhicheng Lei, Chuanfen Wan, Chaomin BMC Pediatr Case Report BACKGROUND: Paragonimiasis, particularly hepatic paragonimiasis (HP), is a type of zoonotic parasitic disease rarely encountered in infants. There have been only a few reports of HP, and no case of HP has been reported in an infant. CASE PRESENTATION: A 15-month-old girl presented with persistent mild fever with a duration of 1 month, hepatomegaly, and low-density lesions in the right hepatic lobe on abdominal ultrasound and computer tomography. Pathological examination and serum antibody detection were performed to verify HP. The diagnosis of HP was established based on findings of Charcot-Leyden crystals on liver lesion biopsy and antibodies against paragonimus westermani detected by enzyme-linked immunosorbent assay. After initiation of praziquantel (75 mg/kg/day for 3 days), all clinical findings promptly improved and the patient was discharged. CONCLUSION: It is very important to consider paragonimiasis in the clinical examination of infants from an area with paragonimiasis epidemic presenting with fever, hepatomegaly, low-density lesions in the liver. BioMed Central 2017-11-15 /pmc/articles/PMC5688620/ /pubmed/29141594 http://dx.doi.org/10.1186/s12887-017-0942-5 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Gong, Zongrong
Xu, Zhicheng
Lei, Chuanfen
Wan, Chaomin
Hepatic paragonimiasis in a 15-month-old girl: a case report
title Hepatic paragonimiasis in a 15-month-old girl: a case report
title_full Hepatic paragonimiasis in a 15-month-old girl: a case report
title_fullStr Hepatic paragonimiasis in a 15-month-old girl: a case report
title_full_unstemmed Hepatic paragonimiasis in a 15-month-old girl: a case report
title_short Hepatic paragonimiasis in a 15-month-old girl: a case report
title_sort hepatic paragonimiasis in a 15-month-old girl: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688620/
https://www.ncbi.nlm.nih.gov/pubmed/29141594
http://dx.doi.org/10.1186/s12887-017-0942-5
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