Cargando…

A novel GIT2-BRAF fusion in pilocytic astrocytoma

BACKGROUND: KIAA1549-BRAF fusion is the most common genetic event in pilocytic astrocytoma (PA), and leads to activation of the mitogen activated protein kinase (MAPK) signaling pathway. Fusions of BRAF with other partner genes, as well as other genetic alterations not involving BRAF but also leadin...

Descripción completa

Detalles Bibliográficos
Autores principales: Helgager, Jeffrey, Lidov, Hart G., Mahadevan, Navin R., Kieran, Mark W., Ligon, Keith L., Alexandrescu, Sanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688665/
https://www.ncbi.nlm.nih.gov/pubmed/29141672
http://dx.doi.org/10.1186/s13000-017-0669-5