Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway

BACKGROUND: In this study, we investigated the mechanism of platelet activation in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), as well as the activation of the alternative complement pathway by platelets in AAV. METHODS: CD62P and platelet-leukocyte aggregat...

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Detalles Bibliográficos
Autores principales: Miao, Di, Li, Dan-Yang, Chen, Min, Zhao, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688714/
https://www.ncbi.nlm.nih.gov/pubmed/29141676
http://dx.doi.org/10.1186/s13075-017-1458-y

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