Cargando…

Resternotomy does not adversely affect outcome after left ventricular assist device implantation

BACKGROUND: Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that...

Descripción completa

Detalles Bibliográficos
Autores principales: Papathanasiou, Maria, Tsourelis, Loukas, Pizanis, Nikolaus, Koch, Achim, Kamler, Markus, Rassaf, Tienush, Luedike, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688731/
https://www.ncbi.nlm.nih.gov/pubmed/29141690
http://dx.doi.org/10.1186/s40001-017-0289-2
_version_ 1783279226783268864
author Papathanasiou, Maria
Tsourelis, Loukas
Pizanis, Nikolaus
Koch, Achim
Kamler, Markus
Rassaf, Tienush
Luedike, Peter
author_facet Papathanasiou, Maria
Tsourelis, Loukas
Pizanis, Nikolaus
Koch, Achim
Kamler, Markus
Rassaf, Tienush
Luedike, Peter
author_sort Papathanasiou, Maria
collection PubMed
description BACKGROUND: Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that history of cardiac surgery is a risk factor for mortality. Our study investigates the prognostic significance of resternotomy in a homogenous cohort of left ventricular assist device (LVAD) recipients. METHODS: The study included adult patients receiving a continuous-flow LVAD at our institution during the period 2010–2016. Postoperative adverse events and length of stay were analyzed. Survival was assessed at 6 months and by the end of the study. Multivariate risk factor analysis was conducted for independent predictors of death. RESULTS: One hundred twelve patients, who received an intrapericardial LVAD (HVAD, HeartWare), were included in our analysis. Twenty-four patients (21.4%) had a history of previous sternotomy. These patients were older and non-eligible for bridging, and had more frequently coronary heart disease. Univariate analysis demonstrated no differences in the observed complications postoperatively. Survival was similar among groups. Destination therapy was the only predictor of mortality in our analysis (p = 0.02). CONCLUSIONS: Resternotomy was not associated with worse outcomes after LVAD implantation in our cohort.
format Online
Article
Text
id pubmed-5688731
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-56887312017-11-24 Resternotomy does not adversely affect outcome after left ventricular assist device implantation Papathanasiou, Maria Tsourelis, Loukas Pizanis, Nikolaus Koch, Achim Kamler, Markus Rassaf, Tienush Luedike, Peter Eur J Med Res Research BACKGROUND: Resternotomy in cardiac surgery is considered a risk factor for postoperative complications. Previous studies have demonstrated an ambiguous relationship between resternotomy and clinical outcomes. Registry data from a mixed population of durable circulatory support devices suggest that history of cardiac surgery is a risk factor for mortality. Our study investigates the prognostic significance of resternotomy in a homogenous cohort of left ventricular assist device (LVAD) recipients. METHODS: The study included adult patients receiving a continuous-flow LVAD at our institution during the period 2010–2016. Postoperative adverse events and length of stay were analyzed. Survival was assessed at 6 months and by the end of the study. Multivariate risk factor analysis was conducted for independent predictors of death. RESULTS: One hundred twelve patients, who received an intrapericardial LVAD (HVAD, HeartWare), were included in our analysis. Twenty-four patients (21.4%) had a history of previous sternotomy. These patients were older and non-eligible for bridging, and had more frequently coronary heart disease. Univariate analysis demonstrated no differences in the observed complications postoperatively. Survival was similar among groups. Destination therapy was the only predictor of mortality in our analysis (p = 0.02). CONCLUSIONS: Resternotomy was not associated with worse outcomes after LVAD implantation in our cohort. BioMed Central 2017-11-15 /pmc/articles/PMC5688731/ /pubmed/29141690 http://dx.doi.org/10.1186/s40001-017-0289-2 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Papathanasiou, Maria
Tsourelis, Loukas
Pizanis, Nikolaus
Koch, Achim
Kamler, Markus
Rassaf, Tienush
Luedike, Peter
Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title_full Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title_fullStr Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title_full_unstemmed Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title_short Resternotomy does not adversely affect outcome after left ventricular assist device implantation
title_sort resternotomy does not adversely affect outcome after left ventricular assist device implantation
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688731/
https://www.ncbi.nlm.nih.gov/pubmed/29141690
http://dx.doi.org/10.1186/s40001-017-0289-2
work_keys_str_mv AT papathanasioumaria resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT tsourelisloukas resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT pizanisnikolaus resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT kochachim resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT kamlermarkus resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT rassaftienush resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation
AT luedikepeter resternotomydoesnotadverselyaffectoutcomeafterleftventricularassistdeviceimplantation