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Polymorphisms at microRNA binding sites of Ara-C and anthracyclines-metabolic pathway genes are associated with outcome of acute myeloid leukemia patients

BACKGROUND: Gene polymorphisms at microRNA-binding sites (poly-miRTS) may affect gene transcription and expression through miRNA regulation, which is associated with cancer susceptibility, sensitivity to chemotherapy and prognosis. This study investigated the association between poly-miRTS of Ara-C/...

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Detalles Bibliográficos
Autores principales:	Cao, Hai-xia, Miao, Chao-feng, Yan, Liang, Tang, Ping, Zhang, Li-rong, Sun, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688732/ https://www.ncbi.nlm.nih.gov/pubmed/29141648 http://dx.doi.org/10.1186/s12967-017-1339-9

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