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Methylxanthines induce structural and functional alterations of the cardiac system in zebrafish embryos

BACKGROUND: Zebrafish embryos are emerging as a model for pharmacological and toxicological studies. We used zebrafish embryos to study the general toxicity and cardiovascular effects of eight methylxanthines: aminophylline, caffeine, diprophylline, doxofylline, etophylline, 3-isobutyl-1-methylxanth...

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Detalles Bibliográficos
Autores principales:	Basnet, Ram Manohar, Zizioli, Daniela, Guarienti, Michela, Finazzi, Dario, Memo, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688754/ https://www.ncbi.nlm.nih.gov/pubmed/29141695 http://dx.doi.org/10.1186/s40360-017-0179-9

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