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DNPEP is not the only peptidase that produces SPAK fragments in kidney
SPAK (STE20/SPS1‐related proline/alanine‐rich kinase) regulates Na(+) and Cl(−) reabsorption in the distal convoluted tubule, and possibly in the thick ascending limb of Henle. This kinase phosphorylates and activates the apical Na‐Cl cotransporter in the DCT. Western blot analysis reveals that SPAK...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688775/ https://www.ncbi.nlm.nih.gov/pubmed/29122955 http://dx.doi.org/10.14814/phy2.13479 |