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DNPEP is not the only peptidase that produces SPAK fragments in kidney

SPAK (STE20/SPS1‐related proline/alanine‐rich kinase) regulates Na(+) and Cl(−) reabsorption in the distal convoluted tubule, and possibly in the thick ascending limb of Henle. This kinase phosphorylates and activates the apical Na‐Cl cotransporter in the DCT. Western blot analysis reveals that SPAK...

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Detalles Bibliográficos
Autores principales:	Koumangoye, Rainelli, Delpire, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688775/ https://www.ncbi.nlm.nih.gov/pubmed/29122955 http://dx.doi.org/10.14814/phy2.13479

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