Changes in vasoactive pathways in congenital diaphragmatic hernia associated pulmonary hypertension explain unresponsiveness to pharmacotherapy

BACKGROUND: Patients with congenital diaphragmatic hernia (CDH) have structural and functional different pulmonary vessels, leading to pulmonary hypertension. They often fail to respond to standard vasodilator therapy targeting the major vasoactive pathways, causing a high morbidity and mortality. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Mous, Daphne S., Buscop-van Kempen, Marjon J., Wijnen, Rene M. H., Tibboel, Dick, Rottier, Robbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688796/
https://www.ncbi.nlm.nih.gov/pubmed/29115963
http://dx.doi.org/10.1186/s12931-017-0670-2

Ejemplares similares

Ejemplares similares