STAT3-blocked whole-cell hepatoma vaccine induces cellular and humoral immune response against HCC

BACKGROUND: Whole-cell tumor vaccines have shown much promise; however, only limited success has been achieved for the goal of eliciting robust tumor-specific T-cell responses. METHODS: Hepatocellular carcinoma (HCC) cells, H22 and Hepa1–6, were modified by blocking the STAT3 signaling pathway with...

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Detalles Bibliográficos
Autores principales: Han, Qiuju, Wang, Yaqun, Pang, Min, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688805/
https://www.ncbi.nlm.nih.gov/pubmed/29115974
http://dx.doi.org/10.1186/s13046-017-0623-0

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