A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature

Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after the initiation of CBZ. We establish the probability of drug-induced liver injury using Council for...

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Autores principales: Ganesh, Suhas, Shukla, Lekhansh, Kandasamy, Arun, Benegal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688903/
https://www.ncbi.nlm.nih.gov/pubmed/29200572
http://dx.doi.org/10.4103/IJPSYM.IJPSYM_19_17
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author Ganesh, Suhas
Shukla, Lekhansh
Kandasamy, Arun
Benegal, Vivek
author_facet Ganesh, Suhas
Shukla, Lekhansh
Kandasamy, Arun
Benegal, Vivek
author_sort Ganesh, Suhas
collection PubMed
description Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after the initiation of CBZ. We establish the probability of drug-induced liver injury using Council for International Organizations of Medical Sciences/Roussel Uclaf Causality Assessment Method causality assessment scale, and the patient had high probability with a score of 9. We briefly review the literature in this field discussing the scope of the problem, etiopathogenesis, clinical manifestation, course, and management.
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spelling pubmed-56889032017-12-01 A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature Ganesh, Suhas Shukla, Lekhansh Kandasamy, Arun Benegal, Vivek Indian J Psychol Med Case Report Carbamazepine (CBZ) is one of the widely prescribed drugs in the field of neuropsychiatry. We report a case of a 27-year-old female patient presenting with severe cholestatic hepatitis presenting after the initiation of CBZ. We establish the probability of drug-induced liver injury using Council for International Organizations of Medical Sciences/Roussel Uclaf Causality Assessment Method causality assessment scale, and the patient had high probability with a score of 9. We briefly review the literature in this field discussing the scope of the problem, etiopathogenesis, clinical manifestation, course, and management. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5688903/ /pubmed/29200572 http://dx.doi.org/10.4103/IJPSYM.IJPSYM_19_17 Text en Copyright: © 2017 Indian Journal of Psychological Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ganesh, Suhas
Shukla, Lekhansh
Kandasamy, Arun
Benegal, Vivek
A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title_full A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title_fullStr A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title_full_unstemmed A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title_short A Case of Carbamazepine-induced Severe Cholestatic Hepatitis: Case Report and Review of Literature
title_sort case of carbamazepine-induced severe cholestatic hepatitis: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688903/
https://www.ncbi.nlm.nih.gov/pubmed/29200572
http://dx.doi.org/10.4103/IJPSYM.IJPSYM_19_17
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