Downregulation of MiR-31 stimulates expression of LATS2 via the hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma

BACKGROUND: Dysregulation of miRNAs is associated with cancer development by coordinately suppressing abundant target genes. Emerging evidence indicates that miR-31 plays a dual role in tumorigenicity. However, whether miR-31 plays as an oncogene in esophageal squamous cell carcinoma (ESCC) and the...

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Detalles Bibliográficos
Autores principales: Gao, Yanping, Yi, Jun, Zhang, Kai, Bai, Fan, Feng, Bing, Wang, Rui, Chu, Xiaoyuan, Chen, Longbang, Song, Haizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689139/
https://www.ncbi.nlm.nih.gov/pubmed/29145896
http://dx.doi.org/10.1186/s13046-017-0622-1

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