ANAT 2.0: reconstructing functional protein subnetworks

BACKGROUND: ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a number of organisms including yeast and human. RESULTS: Here we report on a ne...

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Autores principales: Almozlino, Yomtov, Atias, Nir, Silverbush, Dana, Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689176/
https://www.ncbi.nlm.nih.gov/pubmed/29145805
http://dx.doi.org/10.1186/s12859-017-1932-1
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author Almozlino, Yomtov
Atias, Nir
Silverbush, Dana
Sharan, Roded
author_facet Almozlino, Yomtov
Atias, Nir
Silverbush, Dana
Sharan, Roded
author_sort Almozlino, Yomtov
collection PubMed
description BACKGROUND: ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a number of organisms including yeast and human. RESULTS: Here we report on a new version of the tool, ANAT 2.0, which introduces substantial code and database updates as well as several new network reconstruction algorithms that greatly extend the applicability of the tool to biological data sets. CONCLUSIONS: ANAT 2.0 is an up-to-date network reconstruction tool that addresses several reconstruction challenges across multiple species.
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spelling pubmed-56891762017-11-24 ANAT 2.0: reconstructing functional protein subnetworks Almozlino, Yomtov Atias, Nir Silverbush, Dana Sharan, Roded BMC Bioinformatics Software BACKGROUND: ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a number of organisms including yeast and human. RESULTS: Here we report on a new version of the tool, ANAT 2.0, which introduces substantial code and database updates as well as several new network reconstruction algorithms that greatly extend the applicability of the tool to biological data sets. CONCLUSIONS: ANAT 2.0 is an up-to-date network reconstruction tool that addresses several reconstruction challenges across multiple species. BioMed Central 2017-11-16 /pmc/articles/PMC5689176/ /pubmed/29145805 http://dx.doi.org/10.1186/s12859-017-1932-1 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Almozlino, Yomtov
Atias, Nir
Silverbush, Dana
Sharan, Roded
ANAT 2.0: reconstructing functional protein subnetworks
title ANAT 2.0: reconstructing functional protein subnetworks
title_full ANAT 2.0: reconstructing functional protein subnetworks
title_fullStr ANAT 2.0: reconstructing functional protein subnetworks
title_full_unstemmed ANAT 2.0: reconstructing functional protein subnetworks
title_short ANAT 2.0: reconstructing functional protein subnetworks
title_sort anat 2.0: reconstructing functional protein subnetworks
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689176/
https://www.ncbi.nlm.nih.gov/pubmed/29145805
http://dx.doi.org/10.1186/s12859-017-1932-1
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