Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus)

BACKGROUND: The de novo assembly of repeat-rich mammalian genomes using only high-throughput short read sequencing data typically results in highly fragmented genome assemblies that limit downstream applications. Here, we present an iterative approach to hybrid de novo genome assembly that incorpora...

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Detalles Bibliográficos
Autores principales: Larsen, Peter A., Harris, R. Alan, Liu, Yue, Murali, Shwetha C., Campbell, C. Ryan, Brown, Adam D., Sullivan, Beth A., Shelton, Jennifer, Brown, Susan J., Raveendran, Muthuswamy, Dudchenko, Olga, Machol, Ido, Durand, Neva C., Shamim, Muhammad S., Aiden, Erez Lieberman, Muzny, Donna M., Gibbs, Richard A., Yoder, Anne D., Rogers, Jeffrey, Worley, Kim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689209/
https://www.ncbi.nlm.nih.gov/pubmed/29145861
http://dx.doi.org/10.1186/s12915-017-0439-6

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