A suspicious case of cefmetazole‐induced hypoprothrombinemia

Cefmetazole occasionally prolongs the prothrombin time. The mechanism is considered to be because of (i) inhibition of vitamin K metabolism, (ii) a lack of vitamin K, and (iii) low vitamin K stores. We report the death of a 93‐year‐old woman who was administered cefmetazole and exhibited a prolonged...

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Detalles Bibliográficos
Autores principales: Kodama, Nobuhiro, Matsumoto, Shuichi, Matsubayashi, Sunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689430/
https://www.ncbi.nlm.nih.gov/pubmed/29264036
http://dx.doi.org/10.1002/jgf2.18
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author Kodama, Nobuhiro
Matsumoto, Shuichi
Matsubayashi, Sunao
author_facet Kodama, Nobuhiro
Matsumoto, Shuichi
Matsubayashi, Sunao
author_sort Kodama, Nobuhiro
collection PubMed
description Cefmetazole occasionally prolongs the prothrombin time. The mechanism is considered to be because of (i) inhibition of vitamin K metabolism, (ii) a lack of vitamin K, and (iii) low vitamin K stores. We report the death of a 93‐year‐old woman who was administered cefmetazole and exhibited a prolonged prothrombin time. When using cefmetazole in elderly patients, PT‐INR should be monitored every few days.
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spelling pubmed-56894302017-12-20 A suspicious case of cefmetazole‐induced hypoprothrombinemia Kodama, Nobuhiro Matsumoto, Shuichi Matsubayashi, Sunao J Gen Fam Med Case Reports Cefmetazole occasionally prolongs the prothrombin time. The mechanism is considered to be because of (i) inhibition of vitamin K metabolism, (ii) a lack of vitamin K, and (iii) low vitamin K stores. We report the death of a 93‐year‐old woman who was administered cefmetazole and exhibited a prolonged prothrombin time. When using cefmetazole in elderly patients, PT‐INR should be monitored every few days. John Wiley and Sons Inc. 2017-06-21 /pmc/articles/PMC5689430/ /pubmed/29264036 http://dx.doi.org/10.1002/jgf2.18 Text en © 2017 Fukuoka Tokushukai Medical Center. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Kodama, Nobuhiro
Matsumoto, Shuichi
Matsubayashi, Sunao
A suspicious case of cefmetazole‐induced hypoprothrombinemia
title A suspicious case of cefmetazole‐induced hypoprothrombinemia
title_full A suspicious case of cefmetazole‐induced hypoprothrombinemia
title_fullStr A suspicious case of cefmetazole‐induced hypoprothrombinemia
title_full_unstemmed A suspicious case of cefmetazole‐induced hypoprothrombinemia
title_short A suspicious case of cefmetazole‐induced hypoprothrombinemia
title_sort suspicious case of cefmetazole‐induced hypoprothrombinemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689430/
https://www.ncbi.nlm.nih.gov/pubmed/29264036
http://dx.doi.org/10.1002/jgf2.18
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