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Induction of DISE in ovarian cancer cells in vivo

The death receptor CD95/Fas can be activated by immune cells to kill cancer cells. shRNAs and siRNAs derived from CD95 or CD95 ligand (CD95L) are highly toxic to most cancer cells. We recently found that these sh/siRNAs kill cancer cells in the absence of the target by targeting the 3’UTRs of critic...

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Detalles Bibliográficos
Autores principales:	Murmann, Andrea E., McMahon, Kaylin M., Haluck-Kangas, Ashley, Ravindran, Nandini, Patel, Monal, Law, Calvin Y., Brockway, Sonia, Wei, Jian-Jun, Thaxton, C. Shad, Peter, Marcus E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689563/ https://www.ncbi.nlm.nih.gov/pubmed/29156673 http://dx.doi.org/10.18632/oncotarget.21471

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