The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland

Histone modification alters chromatin architecture to regulate gene transcription. KDM3A is a histone demethylase in the JmjC domain-containing protein family. It removes di- and mono- methyl residues from di- or mono-methylated lysine 9 of histone H3 (H3K9me2/me1). Recent studies have shown that Kd...

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Detalles Bibliográficos
Autores principales: Qin, Li, Xu, Yixiang, Yu, Xiaobin, Toneff, Michael J., Li, Dabing, Liao, Lan, Martinez, Jarrod D., Li, Yi, Xu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689571/
https://www.ncbi.nlm.nih.gov/pubmed/29156681
http://dx.doi.org/10.18632/oncotarget.21380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689571/
https://www.ncbi.nlm.nih.gov/pubmed/29156681
http://dx.doi.org/10.18632/oncotarget.21380

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