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Interaction of microRNA-21/145 and Smad3 domain-specific phosphorylation in hepatocellular carcinoma

MicroRNAs 21 and 145 exhibit inverse expression in Hepatocellular carcinoma (HCC), but how they relate to Smad3 C-terminal and Link region phosphorylation (pSmad3C and pSmad3L) downstream of TGF-β/MAPK signaling, remains inconclusive. Our results suggest microRNA-145 targets Smad3 in HepG2 cells. De...

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Detalles Bibliográficos
Autores principales:	Wang, Ji Yu, Fang, Meng, Boye, Alex, Wu, Chao, Wu, Jia Jun, Ma, Ying, Hou, Shu, Kan, Yue, Yang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689586/ https://www.ncbi.nlm.nih.gov/pubmed/29156696 http://dx.doi.org/10.18632/oncotarget.17709

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