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Exploring brusatol as a new anti-pancreatic cancer adjuvant: biological evaluation and mechanistic studies

Pancreatic cancer is highly resistant to chemotherapeutic agents and is known to have a poor prognosis. The development of new therapeutic entities is badly needed for this deadly malignancy. In this study, we demonstrated for the first time that brusatol, a natural quassinoid isolated from a Chines...

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Detalles Bibliográficos
Autores principales: Lu, Zheng, Lai, Zheng-Quan, Leung, Albert W.N., Leung, Po Sing, Li, Zhao-Shen, Lin, Zhi-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689587/
https://www.ncbi.nlm.nih.gov/pubmed/29156697
http://dx.doi.org/10.18632/oncotarget.17761