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Post-surgery fluids promote transition of cancer stem cell-to-endothelial and AKT/mTOR activity, contributing to relapse of giant cell tumors of bone

Giant cell tumors of bone (GCTB) are rare sarcomas with a high rate of unpredictable local relapse. Studies suggest that surgical methods affect recurrence, supporting the idea that local disease develops from re-growth of residual cancer cells. To identify early prognostic markers of individual ris...

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Detalles Bibliográficos
Autores principales: Fazioli, Flavio, Colella, Gianluca, Miceli, Roberta, Di Salvatore, Mariano Giuseppe, Gallo, Michele, Boccella, Serena, De Chiara, Annarosaria, Ruosi, Carlo, de Nigris, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689592/
https://www.ncbi.nlm.nih.gov/pubmed/29156702
http://dx.doi.org/10.18632/oncotarget.18783