Cargando…
The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo
Cisplatin (CDDP) has been shown to be a promising anticancer drug that is effective against many types of cancer, which include osteosarcoma (OS). However, its therapeutic application is restricted by its toxicity in normal tissues and by side effects caused in patients. Reduction of the toxicity of...
Autores principales: | Dai, Guo, Yu, Ling, Yang, Jian, Xia, Kezhou, Zhang, Zhengpei, Liu, Gaiwei, Gao, Tian, Guo, Weichun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689600/ https://www.ncbi.nlm.nih.gov/pubmed/29156710 http://dx.doi.org/10.18632/oncotarget.19554 |
Ejemplares similares
-
Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells
por: Zhang, Zhengpei, et al.
Publicado: (2017) -
Cisplatin promotes mesenchymal-like characteristics in osteosarcoma through Snail
por: Fang, Shuo, et al.
Publicado: (2016) -
Notch signaling is important for epithelial-mesenchymal transition induced by low concentrations of doxorubicin in osteosarcoma cell lines
por: Yang, Jian, et al.
Publicado: (2017) -
Cisplatin-resistant osteosarcoma cells possess cancer stem cell properties in a mouse model
por: Yang, Jian, et al.
Publicado: (2016) -
miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1
por: Guo, Xiaodong, et al.
Publicado: (2017)