Hepatitis C virus Core overcomes all-trans retinoic acid-induced apoptosis in human hepatoma cells by inhibiting p14 expression via DNA methylation

All-trans retinoic acid (ATRA), the most biologically active metabolite of vitamin A, is known to induce p14 expression via promoter hypomethylation to activate the p14-MDM2-p53 pathway, which leads to activation of the p53-dependent apoptotic pathway and subsequent induction of apoptosis in human h...

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Detalles Bibliográficos
Autores principales: Kwak, Juri, Choi, Jung-Hye, Jang, Kyung Lib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689633/
https://www.ncbi.nlm.nih.gov/pubmed/29156743
http://dx.doi.org/10.18632/oncotarget.20337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689633/
https://www.ncbi.nlm.nih.gov/pubmed/29156743
http://dx.doi.org/10.18632/oncotarget.20337

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