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Network-directed cis-mediator analysis of normal prostate tissue expression profiles reveals downstream regulatory associations of prostate cancer susceptibility loci
Large-scale genome-wide association studies have identified multiple single-nucleotide polymorphisms associated with risk of prostate cancer. Many of these genetic variants are presumed to be regulatory in nature; however, follow-up expression quantitative trait loci (eQTL) association studies have...
Autores principales: | Larson, Nicholas B., McDonnell, Shannon K., Fogarty, Zach, Larson, Melissa C., Cheville, John, Riska, Shaun, Baheti, Saurabh, Weber, Alexandra M., Nair, Asha A., Wang, Liang, O’Brien, Daniel, Davila, Jaime, Schaid, Daniel J., Thibodeau, Stephen N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689655/ https://www.ncbi.nlm.nih.gov/pubmed/29156765 http://dx.doi.org/10.18632/oncotarget.20717 |
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