JQ1 synergizes with the Bcl-2 inhibitor ABT-263 against MYCN-amplified small cell lung cancer

Small cell lung cancer (SCLC) is a clinically aggressive cancer with very poor prognosis. Amplification of MYC family genes and overexpression of Bcl-2 protein are common in SCLC, and they are likely therapeutic targets for SCLC. Previous clinical study showed that single agent targeting Bcl-2 with...

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Detalles Bibliográficos
Autores principales: Wang, Huogang, Hong, Bo, Li, Xuemin, Deng, Ke, Li, Hong, Yan Lui, Vivian Wai, Lin, Wenchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689687/
https://www.ncbi.nlm.nih.gov/pubmed/29156797
http://dx.doi.org/10.18632/oncotarget.21146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689687/
https://www.ncbi.nlm.nih.gov/pubmed/29156797
http://dx.doi.org/10.18632/oncotarget.21146

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