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37 kDa LRP::FLAG enhances telomerase activity and reduces senescent markers in vitro

One of the core regulators of cellular aging are telomeres, repetitive DNA sequences at the ends of chromosomes that are maintained by the ribonucleoprotein DNA polymerase complex, telomerase. Recently, we demonstrated that knockdown of the 37kDa/ 67kDa laminin receptor (LRP/LR), a protein that prom...

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Detalles Bibliográficos
Autores principales:	Otgaar, Tyrone C., Ferreira, Eloise, Malindisa, Sibusiso, Bernert, Martin, Letsolo, Boitelo T., Weiss, Stefan F.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689714/ https://www.ncbi.nlm.nih.gov/pubmed/29156824 http://dx.doi.org/10.18632/oncotarget.21278

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