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Tracheal Replacement Therapy with a Stem Cell‐Seeded Graft: Lessons from Compassionate Use Application of a GMP‐Compliant Tissue‐Engineered Medicine

Tracheal replacement for the treatment of end‐stage airway disease remains an elusive goal. The use of tissue‐engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell‐seeded, decellularized tissue‐engineered tracheal graft was used on a comp...

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Detalles Bibliográficos
Autores principales: Elliott, Martin J., Butler, Colin R., Varanou‐Jenkins, Aikaterini, Partington, Leanne, Carvalho, Carla, Samuel, Edward, Crowley, Claire, Lange, Peggy, Hamilton, Nicholas J., Hynds, Robert E., Ansari, Tahera, Sibbons, Paul, Fierens, Anja, McLaren, Claire, Roebuck, Derek, Wallis, Colin, Muthialu, Nagarajan, Hewitt, Richard, Crabbe, David, Janes, Sam M., De Coppi, Paolo, Lowdell, Mark W., Birchall, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689750/
https://www.ncbi.nlm.nih.gov/pubmed/28544662
http://dx.doi.org/10.1002/sctm.16-0443