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Tracheal Replacement Therapy with a Stem Cell‐Seeded Graft: Lessons from Compassionate Use Application of a GMP‐Compliant Tissue‐Engineered Medicine
Tracheal replacement for the treatment of end‐stage airway disease remains an elusive goal. The use of tissue‐engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell‐seeded, decellularized tissue‐engineered tracheal graft was used on a comp...
Autores principales: | Elliott, Martin J., Butler, Colin R., Varanou‐Jenkins, Aikaterini, Partington, Leanne, Carvalho, Carla, Samuel, Edward, Crowley, Claire, Lange, Peggy, Hamilton, Nicholas J., Hynds, Robert E., Ansari, Tahera, Sibbons, Paul, Fierens, Anja, McLaren, Claire, Roebuck, Derek, Wallis, Colin, Muthialu, Nagarajan, Hewitt, Richard, Crabbe, David, Janes, Sam M., De Coppi, Paolo, Lowdell, Mark W., Birchall, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689750/ https://www.ncbi.nlm.nih.gov/pubmed/28544662 http://dx.doi.org/10.1002/sctm.16-0443 |
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